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apo-enzyme

apo-enzyme Chem.
  (ˌæpəʊˈɛnzaɪm)
  [a. F. apoenzyme, f. apo- + enzyme 2.]
  (See quot. 1961.)

[1936 Union Internat. de Chimie Compt. Rend. 43 Le complexe total sera appelé holoenzyme et le résidu, après séparation de ses activateurs, sera appelé apoenzyme.] 1936 Chem. Abstr. 6397 A comprehensive treatise discussing..character and action of coenzymes and apoenzymes. 1944 Jrnl. Pharm. & Exp. Therap. LXXXI. 246 This enzyme like substance appears to attack the apoenzyme or protein part of the oxidative enzyme system. 1950 [see co-enzyme]. 1961 Brit. Med. Dict. 123/2 Apo-enzyme, the protein carrier, or enzyme proper (e.g. carboxylase) which, with a co-enzyme (co-carboxylase), carries out an enzymic reaction.

Oxford English Dictionary

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