Artificial intelligent assistant

coloboma

coloboma Path.
  (kɒləʊˈbəʊmə)
  [mod.L., a. Gr. κολόβωµα the part removed in mutilation, f. κολοβός curtailed.]
  A malformation or mutilation of an organ; spec. a defect in the iris of the eye, due to imperfect closure of the choroidal fissure.

1843 tr. J. Müller's Elem. Phys. II. 1631 The Coloboma seems to arise from the imperfect development of the iris in the situation of the fissure of the choroid. 1875 H. Walton Dis. Eye 724 Coloboma is the rarest of congenital malformations. 1879 P. Smith Glaucoma 178 The portions of these membranes occupying the pupil and the coloboma.

Oxford English Dictionary

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