propranolol Pharm.
(prəʊˈprænəlɒl)
[f. propyl + propanol with reduplication of final -ol.]
The compound 1-isopropylamino-3-(1-naphthyloxy)-2-propanol, C16H21NO2, which is a β-adrenergic blocking agent used mainly (in the form of a colourless crystalline hydrochloride) in the treatment of cardiac arrhythmia.
| 1964 Brit. Med. Jrnl. 19 Sept. 720 (heading) Effect of propranolol (Inderal) in angina pectoris: preliminary report. 1965 J. H. Burn Lect. Notes Pharmacol. (ed. 8) 10 When propranolol is given, a patient performs a given amount of work at a lower heart rate and he can perform a greater amount of work without feeling pain. 1972 Lancet 16 Sept. 565/2 In our clinical experience, propranolol is effective in the treatment of heroin dependence. 1974 Sci. Amer. June 62/3 This complex series of events can be turned off by propranolol, a drug that prevents the noradrenaline from combining with the beta adrenergic receptor. 1980 Brit. Med. Jrnl. 29 Mar. 885/1 We have..investigated the effect of giving higher doses of a nonselective beta-blocker (propranolol)..to patients with suspected myocardial infarction. |