œstrone Biochem.
(ˈiːs-, ˈɛstrəʊn)
Also (U.S.) estr-.
[f. œstrane + -one.]
An œstrogenic hormone, C18H22O2, obtained from the urine of pregnant women and mares with actions and uses similar to those of œstradiol.
| 1933 [see œstriol]. 1951 A. Grollman Pharmacol. & Therapeutics xxvi. 579 Several preparations of amorphous concentrates of pregnancy urine or placental tissue, which consist principally of estrone sulfate, are prepared commercially for oral use. 1958 Sci. News XLVII. 87 Oestrone was the first naturally occurring oestrogen to be isolated in pure crystalline form. 1968 R. O. C. Norman Princ. Org. Synthesis xix. 651 There are four asymmetric carbon atoms in oestrone, so that there are eight enantiomorphic pairs of stereoisomers, all of which have been synthesized. |