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cocaine

cocaine
  (kəʊˈkeɪn)
  [f. coca + -ine.]
  An important alkaloid obtained from the leaves and young twigs of the coca plant, valuable as a local anæsthesiant, and also used as a stuimulant.

1874 Schorlemmer Manual Carbon Comp. 483 Cocaine (C17H21NO4) is the active principle of the coca-leaves. 1886 Brit. & Col. Druggist 31 July, The valuable alkaloid cocaine, whose properties as a local anæsthetic have created almost a revolution in ophthalmic and other branches of surgery.


attrib. 1887 Braithwaite Retrosp. of Med. XCV. 11 Cocaine Cotton for toothache. Ibid. XCIX. 371 Cocaine anæsthesia.

  Hence, coˈcainize v. to treat or affect with cocaine, to render insensible by means of cocaine; cocainiˈzation, treatment with cocaine; coˈcainism, the chronic condition produced by excessive use of cocaine as a stimulant (cf. alcoholism).

1887 T. L. Brunton Pharmacol. Therap. (ed. 3) 226 Stimulation of [the nerve] produces contraction in the cocainised pupil. 1887 Med. News (Phila.) 30 Apr. 501/2 There is, however, a certain proportion of cases in which cocainization cannot be produced. 1964 S. Duke-Elder Parsons' Dis. Eye (ed. 14) xv. 181 They are common in elderly people and should be removed with a sharp needle after cocainization.

Oxford English Dictionary

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