granuloma Path.
(grænjʊˈləʊmə)
[f. L. grānul-um granule, after the analogy of glaucoma and other words of Gr. origin.]
‘A term invented by Virchow to include certain neoplasms which generally do not advance in structure beyond the stage of granulation tissue, and which usually proceed to ulceration’ (Syd. Soc. Lex. 1886). Also with qualifying L. adj., as granuloma inguinale, a chronic, probably venereal infection produced by the bacterium Calymmatobacterium (Donovania) granulomatis and characterized by creeping granulomatous lesions in the inguinal and genital regions.
| 1861 Bumstead Ven. Dis. (1879) 442 These cells belong to the group called by Virchow granuloma. 1897 Allbutt's Syst. Med. II. 804 In nodular leprosy, however, the granuloma of the skin..[is] characteristic. 1918 Jrnl. Med. Res. Jan. 427 Granuloma inguinale is endemic in certain tropical and subtropical countries. 1957 Encycl. Brit. XXIII. 48/1 In all cases of suspected granuloma inguinale, syphilis should be thoroughly ruled out. |
Hence granuˈlomatous a., of or pertaining to granuloma.
| 1883 MacAlister tr. Ziegler's Pathol. Anat. i. §117. 162 In most of the granulomatous disorders we may have not merely a diffusion of the disease throughout the individual organism, but [etc.]. 1898 P. Manson Trop. Diseases xxvii. 423 A..granulomatous, encrusted eruption. |