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pathophysiology

pathophysiology Med.
  (ˌpæθəʊfɪzɪˈɒlədʒɪ)
  [f. patho- + physiology.]
  The physiological processes associated with disease or injury; the study of such processes.

1952 Adv. Internal Med. V. 428 Abnormalities in protein metabolism form the central problem in the patho⁓physiology of multiple myeloma. 1962 Lancet 2 June 1172/2 An analysis of the pathophysiology of these disturbances may further our understanding of cerebral function. 1972 Ibid. 20 May 1104/1 It is impossible to keep up with all trends in pathophysiology. 1974 M. C. Gerald Pharmacol. xvi. 296 We may anticipate that the etiology of these disorders will be better understood with future advances in the pathophysiology and biochemistry of mental disease. 1975 Nature 3 Jan. 77/2 A symposium on the pathophysiology and clinical aspects of pain.

  Hence ˌpathophysioˈlogic, -physioˈlogical adjs., of or involving abnormal physiological processes; pertaining to pathophysiology, ˌpathophysioˈlogically adv., as regards pathophysiology.

1952 Adv. Internal Med. V. 398 From the pathophysiologic point of view, the most interesting part of the myeloma problem is the disturbance of protein metabolism. 1960 (title) Works of the Institute of Higher Nervous Activity. Pathophysiological series. (Academy of Sciences of the U.S.S.R.) 1962 H. G. Keitel Pathophysiol. & Treatment of Body Fluid Disturbances i. 12 In many illnesses the anatomical, biochemical, and patho⁓physiological characteristics of the associated fluid derangement and their successful treatment have been fairly clearly defined. 1973 Wasserman & Brown in Holland & Frei Cancer Med. xix. 1367/1 The patho⁓physiologic mechanisms responsible for these symptoms. 1973 Sci. Amer. Sept. 121/3 Selective errors in the metabolism of the monamines in specific areas of the brain may be the pathophysiological basis for psychotic disorders. 1976 Nature 29 July 397/2 This..results in a chronic murine hepatosplenic disease which closely resembles, pathophysiologically, human chronic schistosomiasis.

Oxford English Dictionary

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