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vacuolated

vacuolated, ppl. a.
  (ˈvækjuːəleɪtɪd)
  [f. vacuole: cf. vacuolation.]
  Rendered vacuolar; modified or altered by vacuolation.

1859 Huxley Oceanic Hydrozoa 84 The cavity of the base of the involucrum appears to become filled up by vacuolated tissue. 1878 F. J. Bell Gegenbauer's Comp. Anat. 24 There are often vacuolated spaces in the cells, which are filled with a fluid. 1896 Allbutt's Syst. Med. I. 211 Cell invaginations, the protoplasm of which is highly vacuolated.

Oxford English Dictionary

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