vanillyl Chem. and Biochem.
(ˈvænɪlɪl)
[f. vanillic a., -in + -yl.]
The radical, OCH3C6H3(OH)CHvanillylmandelic acid [mandelic a.], the end-product of the metabolism of adrenaline and noradrenaline, measured to test for certain tumours; 4-hydroxy-3-methoxymandelic acid, OCH3C6H3(OH)CH(OH)COOH.
| 1876 Jrnl. Chem. Soc. XXIX. 76 This body, which is still under investigation, is vanillyl alcohol. 1932 Jrnl. Pharmacol. & Exper. Therapeutics XLV. 165 The salts of vanillyl-ethylamine and methylamine were found to be quite soluble. [1957 Armstrong & McMillan in Pharmacol. Rev. XI. 395 Because of the cumbersome nature of the proper name for this compound..the trivial name ‘vanilmandelic acid’ is proposed, and the abbreviation ‘VMA’.] 1961 Clin. Chem. VII. 257 The determination of 3-methoxy-4-hydroxymandelic acid, also called vanillyl⁓mandelic acid (VMA), in urine has recently come into use as a confirmatory test for pleochromocytoma. 1979 Nature 1 Mar. 41/2 Many oxidative degradations have also been carried out to break coal down into simpler species; however, isolation and identification of p-hydroxyl (IV), vanillyl (V), and syringyl (VI) groups, which are characteristic lignin oxidation products, have not yet been confirmed. 1979 Jrnl. R. Soc. Med. LXXII. 533 Twenty-four hour urinary vanillylmandelic acid (VMA) estimations were within normal limits. |