parathormone Physiol.
(pærəˈθɔːməʊn)
[Blend of parath(yroid (s.v. para-1 1) and hormone.]
A polypeptide hormone secreted by the parathyroid glands of higher vertebrates, which increases the amount of calcium in the blood by its action on bones, kidneys, and gut.
Registered in the U.S.A. as a proprietary name, although its protection lapsed in 1966.
| 1925 Official Gaz. (U.S. Patent Office) 17 Nov. 591/1 Eli Lilly & Company, Indianapolis, Ind. Filed Oct. 1, 1925. Para-thor-mone... Medicine or Pharmaceutical Preparation. Claims use since Sept. 1, 1925. 1926 Encycl. Brit. III. 147/2 Collip prepared from the [parathyroid] glands an extract, parathormone, which is capable, when injected subcutaneously into parathyroidectomised dogs, of promptly removing the symptoms of tetany. 1948 Martin & Hynes Clinical Endocrinol. v. 101 Parathormone is a protein substance obtainable in solid, but not crystalline, form by acid extraction of fresh parathyroid tissue. 1965 Lee & Knowles Animal Hormones vi. 104 It would appear that the rate of secretion of parathormone is controlled by the level of the blood calcium. |