Pyramidon2 Pharm.
(pɪˈræmɪdɒn)
Also pyr-, -one (-əʊn).
[a. G. pyramidon (W. Filehne 1896, in Berliner klin. Wochenschr. XXXIII. 1061), f. pyrazolon pyrazolone with inserted amid- (see amido-).]
A white crystalline solid used as an anti-pyretic and analgesic; 4-dimethylamino-1, 5-dimethyl-1-phenylpyrazolin-3-one, C13H17N3O.
Formerly a proprietary term in Britain, and still registered as one in the U.S.
| 1898 Jrnl. Chem. Soc. LXXIV. ii. 656 Dimethylamidophenyldimethylpyrazolone, or pyramidone, prepared by Filehne and Spiro, and recommended by them as a substitute for antipyrin..yields bluish-violet colours when oxidised by ferric chloride, nitric and nitrous acids, and the halogens. 1898 Official Gaz. (U.S. Patent Office) 6 Dec. 1582/2 Remedy for certain named disease. Farberwerke, vormals Meister, Lucius & Brüning, Höchst-on-the-Main, Germany... Pyramidon... Used since December, 1896. 1903 Brit. Med. Jrnl. Suppl.: Weekly Epitome of Current Med. Lit. 21 Nov. 79/3 Having heard a good account of pyramidon he proceeded to employ it in a case which he and the nurse were able to observe very closely. 1908 A. Bennett Jrnl. 14 Dec. (1932) I. 300, I..saw a chemist make me a cachet of pyramidon. 1925 W. Gerhardie Polyglots xlix. 358 She took pyramidon for her head, and aspirin for her cold. 1942 R.A.F. Jrnl. 30 May 35 A German industrialist in 1942 testified that in the Rhineland it was almost impossible to buy soothing drugs, like pyramidon, any more. |