isoleucine Biochem.
(aɪsəʊˈl(j)uːsiːn)
[ad. G. isoleucin (F. Ehrlich 1903, in Zeitschr. Ver. d. Deut. Zucker-Ind. LIII. 821), f. iso- iso- b + leucin leucin.]
An amino-acid of which the dextrorotatory or l- form is an essential nutrient and a general constituent of proteins; 1-amino-2-methylvaleric acid, CH3CH2CH(CH3)CH(NH2)COOH.
| 1903 Jrnl. Chem. Soc. LXXXIV. i. 796 The author has isolated leucine and a new compound, d-isoleucine, isomeric with it. d-isoLeucine crystallises in shining rods or leaflets. 1936 Jrnl. Biol. Chem. CXIV. 89 Leucine and isoleucine have been isolated in considerable quantities by extracting the dried, defatted mycelium of Aspergillus syndowi with acetone. 1962 Lancet 6 Jan. 26/1 They demonstrated a marked elevation of four aminoacids in the blood and urine—namely, the three branched-chain aminoacids (leucine, isoleucine, and valine) and also methionine. |