mesterolone, n. Pharm.
(mɛˈstɛrələʊn)
[Prob. f. methyl n. + sterol n. + -one.]
A synthetic androgen which is given orally in the treatment of male hypogonadism, male infertility, and similar conditions; 17β-hydroxy-1α-methyl-5α-androstan-3-one, C20H32O2 .
| 1965 WHO Chron. XIX. 452 Mesterolone. 1966 Arzneimittel-Forschung XVI. 458/2 Mesterolone has a weak progestational activity, like testosterone. 1987 Oxf. Textbk. Med. (ed. 2) I. x. 98/2 There is no sound evidence to prove that the various non-specific therapies that have been employed such as..mesterolone or cooling the scrotum do anything more for the patient than put off the time when he must learn that he is infertile. 1989 Collier & Longmore Oxf. Handbk. Clin. Specialties (ed. 2) i. 58 Oligospermia (<20 million sperm/ml) may respond to tamoxifen 10 mg/12h PO or mesterolone 50 mg/24h PO for three months or the use of clomiphene. |