mephenesin Pharm.
(məˈfɛnəsɪn)
[f. methyl + phenyl + cresol + -in1.]
A colourless crystalline compound, CH3·C6H4O·CH2CH(OH)CH2OH, which is used as a muscle-relaxant in the treatment of spastic, hypertonic, and hyperkinetic conditions, and as a tranquillizer.
| 1952 Brit. Pharmaceut. Codex 1949 Suppl. 40 Mephenesin consists of 3-(2-methylphenoxy)propane-1:2-diol. 1955 Sci. News Let. 16 July 40/3 In the great majority of 109 cases [of cerebral palsy] treated before dental surgery with mephenesin,..the drug produced feelings of well-being and relaxation, and nervousness diminished or disappeared. 1962 J. H. Burn Drugs, Med. & Man xii. 127 Another study was made by other workers to test the claim that the drug mephenesin exerts a specific effect on subjective anxiety and feeling of tension, and also on objective manifestations of this state. 1972 Neuro-pharmacology XI. 733 Amino-oxyacetic acid did not protect rats against the audiogenic seizures that constitute the barbiturate abstinence syndrome whereas mephenesin..did provide protection. |