hexobarbitone Pharm.
(hɛksəʊˈbɑːbɪtəʊn)
[f. hex- (in hexenyl) + -o- + barbitone.]
A short-acting barbiturate, C12H16N2O3, with hypnotic properties; also known by proprietary names, as Evipal, Evipan; loosely, = hexobarbitone sodium, the monosodium derivative of hexobarbitone, a very short-acting and soluble anæsthetic usu. given intravenously or intramuscularly; also called hexobarbitone soluble.
| 1941 Brit. Pharmacopœia 1932 (Add. 3) 8 (heading) Hexobarbitonum... Hexobarbitone. Synonym. Hexobarbital... Hexobarbitone is 5-Δ{p}-cyclohexenyl-5-methyl-N-methyl-barbituric acid. 1943 Brit. Med. Jrnl. 5 June 714/2 Hexobarbitone given by mouth is an excellent hypnotic when there is no pain. Ibid. 20 Nov. 646/1 Cyanosis rapidly became extreme; 0·5 g. of hexobarbitone soluble (evipan sodium) was dissolved in 5 c.cm. of distilled water and administered intravenously. 1952 Martindale's Extra Pharmacopœia (ed. 23) I. 260 Hexobarbitone sodium has largely been superseded by thiopentone sodium which gives greater muscular relaxation. 1962 J. H. Burn Drugs, Med. & Man ix. 98 The substance hexobarbitone could be injected into a vein and the patient went to sleep with no more warning than he had when going to sleep in his own bed. |