In context of the PRO-seq method, "global" can be substituted for "genome-wide". Note that use of the term _global_ is a call-back to the methodological predecessor of PRO-seq, which was called **global run-on sequencing** (GRO-seq).
In context of the PRO-seq method, "global" can be substituted for "genome-wide". Note that use of the term _global_ is a call-back to the methodological predecessor of PRO-seq, which was called **global run-on sequencing** (GRO-seq).