If this is a new deck or you have no knowledge of the cards that have gone before, then there are 3 known cards (your 2 and the dealer's 1 face-up).
If you have an Ace or your total is 11 or less then there is no chance of you busting.
If you have 20 then you will bust on anything but an Ace. If the dealer is **not** showing an Ace then the chance of busting is $\frac{49-3}{49}$. If he is showing an Ace then the chance is $\frac{49-2}{49}$.
The result is similar for 19 (Ace or 2), 18 (Ace, 2 or 3), 17 (Ace, 2, 3 or 4) & 16 (Ace, 2, 3, 4 or 5).
For 12 to 15 you also need to account for the fact that you may be holding some of the "safe" cards (e.g. 9 + 6 eliminates one of the "safe" 6s).
This can be extended to any number of decks.