Let the number of ways to fill the $2 \times N$ grid with $1 \times 2$ tiles be $f(N)$
We will think of the grid as vertical with base 2.
$Case 1$ : We start with one tile placed horizontally (to fill the first row)
Number of ways to fill the rest = $f(N-1)$ since we are left with a $2 \times (N-1)$ grid
$Case 2$ : We start with two tiles placed vertically to fill the first two rows.
Number of ways to fill the rest = $f(N-2)$
These are all the cases, therefore, $$f(N) = f(N-1) + f(N-2), f(1)=1, f(2)=2$$
This is similar to the fibonacci numbers and gives a closed form as:
$$f(N) = {{{\phi^{(N+1)} - (1- \phi)^{(N+1)}} }\over {\sqrt 5}} , \phi ={1+\sqrt 5 \over 2}$$