Yes, it's possible but not obvious how to do it:
* Create the file ~/.gnome2/accels/nemo:
$ mkdir -p ~/.gnome2/accels
$ touch ~/.gnome2/accels/nemo
* Then add the following line in that file (replace "F4" with whatever shortcut you want to use):
(gtk_accel_path "
This worked for me with Nemo 3.6.5 on Ubuntu 18.04.
Source: