The derailleur arm corrects the chain tension with its spring-loaded mechanism. With an IGH you'll need to adjust the tension by moving the wheel as well as the brake to keep it on the disk. In your configuration the axle sits tight against the end of the slot and chain-pull will not misalign the wheel.
With an IGH the axle is only anchored through compression of the QR on the dropouts which may easily be too slight and allow the axle slide forward on a very hard pedal push. A tugnut will avoid that situation.
Edit: Reading into the manual, I just found that it is possible to use the Rohloff in the same manner as a bike with a rear derailleur. You just need their own chain tensionner in place of the RD. It eliminates the need for moving the wheel and the brake. Chain tension is adjusted once and for all with the axle sitting in the full forward position of the slot.