Road bike disc wheel interchangability This may be a duplicate, but I didn't find an answer: Are road bike disc wheelsets interchangable? For example my cx bike has DT Swiss R24 wheels, could I buy a set of Mavic Ksyrium wheels and fit them onto my bike? Thinking about it, the calliper is fixed onto the frame at a certain position, so I imagine this is possible, or is there something to watch out for?

Calliper and disc positions are standard, as are hub widths and fork spacings for disk wheels. Minor adjustments of the calliper's position could be required. There are however several methods for locking the wheels in the fork that will require your attention: traditional quick release or different types of through axles!