If $f$ is the (continuous) mapping $(x,y)\to(x,y,x-y)$ from $\Bbb R^2$ to $\Bbb R^3$, then the joint distribution of $(X,Y,X-Y)$ is the probability measure $Q$ given by $Q(B)=P(f^{-1}(B))$, for Borel sets $B\subset\Bbb R^3$. This provides a rather abstract YES answer to your question.
In your normal example, because $f$ is linear, the vector $(X,Y,X-Y)$ has a (degenerate) joint normal distribution, with zero means and covariance matrix $$ \left[\matrix{\sigma_1^2&\sigma_{12}&\sigma_1^2-\sigma_{12}\cr \sigma_{12}&\sigma_2^2&\sigma_{12}-\sigma_2^2\cr \sigma_1^2-\sigma_{12}&\sigma_{12}-\sigma_2^2&\sigma_1^2+\sigma_2^2-2\sigma_{12}\cr}\right]. $$ ( _Degenerate_ because this covariance matrix has rank at most 2.)