> Let $R$ be a noetherian integral domain of dimension $2$. If $R$ is integrally closed, then $R$ is Cohen-Macaulay.
From Serre's normality criterion we have that $R$ satisfies $(R_1)$ and $(S_2)$.
$(R_1)$ gives that all the localizations of $R$ at height one primes are regular, and therefore Cohen-Macaulay. (In fact, we don't need to use $(R_1)$ in order to prove that $R_{\mathfrak p}$ is Cohen-Macaulay for prime ideals $\mathfrak p$ of height one.)
Now let $\mathfrak p$ be a height two prime ideal of $R$. From $(S_2)$ we get that $\operatorname{depth}R_{\mathfrak p}\ge2=\dim R_{\mathfrak p}$, so $R_{\mathfrak p}$ is Cohen-Macaulay.
$k[x^4,x^3y,xy^3,y^4]$ is $2$-dimensional, _not_ Cohen-Macaulay and _not_ integrally closed.