> So it seems to me that $\mathcal C^{op},Set$ could be a collection of proper classes.
You're right. Each natural transformation $\alpha\colon H_A\to X$ is a class and proper when $Ob(\mathcal C)$ is proper. Therefore $\mathcal C^{op},X$ is apriori a conglomerate, see p 15-16 in Joy of Cats, which is just a extension of the class concept, much as in the same way class was an extension of set. Yoneda's lemma shows that this conglomerate is a small conglomerate and for all practical purposes can be considered a set.