The conditional probability $P(A|B)$ is given by the formula $\frac{P(A\cap B)}{P(B)}$. That numerator is the probability of choosing a vowel that is also in the first half of the alphabet $\left(\frac38\right)$. The denominator is simply the probability of choosing a letter in the first half of the alphabet $\left(\frac58\right)$.
It looks like you tried to use the formula $P(A\cap B)=P(A)P(B)$. That only works for independent events, and in this case, choosing a vowel and choosing a letter in the first half of the alphabet are _not_ independent.