Are you talking about the SAMBA file server in that tutorial? I don't think Streisand would mess with that configuration. If you're trying to access your file server from outside the home, it looks like you'd have a lot of routing considerations to get past all of the security measures in Streisand. I can't answer for sure without a use case and basic config information.
That said, go ahead and try it! Sounds like a great learning experience either way.