I will assume choice, otherwise things get extra messy.
Let $X$ be of cardinality $\kappa$.
* You have at least $2^\kappa$ partitions:
Define $\sim$ on $P(X)$ by $A\sim B\iff A=B\lor A=X\setminus B$. Clearly every equivalence class has two members so there are $2^\kappa$ of them, and all but the class of $\\{\varnothing,X\\}$ define a proper and distinct partition.
* You don't have more than $2^\kappa$ partitions:
Since every partition has at most $\kappa$ parts, we can think about it as a surjection from $\kappa$ onto itself. Of course many functions can define the same partition, but the point is that there are at most $\kappa^\kappa=2^\kappa$ functions from $X$ to itself, including those which are not surjective. Therefore there cannot be more than $2^\kappa$ partitions.
We have, if so, $2^\kappa$ partitions of $X$ whenever $|X|=\kappa$.