By pooling the answers of N. Ozawa here and C. Eckhardt here we can answer "no" :
Indeed, if an operator is unitary equivalent to a banded operator, it generates an exact $C^{*}$-algebra, and there is an irreducible operator generating a non-exact $C^{*}$-algebra.
Conclusion, there is an irreducible operator which is not unitary equivalent to a banded operator.