You can't change the status of network interface because is set to `unmanaged` (`managed=false`). Use `nmcli -p device` to check it.
Edit the global configuration file `/etc/NetworkManager/NetworkManager.conf` as follows:
[main]
plugins=ifupdown,keyfile
[ifupdown]
managed=true
Then:
sudo systemctl restart NetworkManager
Check it through `nmcli`:
nmcli -p device
The you will be able to activate/desactivate the network.