According to the Gentoo Wiki, it is possible in certain circumstances, but probably not desirable:
> It is not possible to RAID10 an existing volume, **nor reshape the RAID10 across more/less PVs** , nor to convert to a different RAID level/linear volume, **It is possible to extend a RAID10 across additional PVs, but they must be added in multiples of the original RAID10** (which will effectively linearly append a new RAID10), **or --alloc anywhere must be specified (which can hurt performance)**. In the above example, 4 additional PVs would be required without --alloc anywhere.
In addition LVM RAID10 is more restricted than the md RAID10 (eg it requires an even number of drives):
> LVM syntax requires the number of PV be multiple of the numbers stripes and mirror, even though RAID10 format does not