and are very similar terms, essentially synonymous with "life" or "lifestyle" or "living", but you do see some differences in usage in writing and online...
in general is used to talk about the way a person lives. What they do daily, how they spend money, leisure activities and so on. It is also, online, used in talking about helpful items or practices for living your life, or about interesting things around town.
can be found on websites and discussions about making a home more homey or comfortable, more beautiful, decorative, or in other words a nicer environment to live in.
I hear the word used more than , but that could be an effect of being a foreigner living in Japan, and Japanese people being careful to simplify their discussions with me...
There is overlap, since the terms are in many ways synonymous, and I am sure a native speaker will have more insight.