Elizabeth doesn't particularly like talking to Mr Collins about how great his marriage to Charlotte is. She is described in the previous paragraph as having to try "to unite civility and truth" \-- this suggests that telling the truth about her feelings would not be polite.
The particular sentence you have bolded says that she was glad his speech about "his domestic comforts" was interrupted when Charlotte herself arrived. It doesn't particularly speak to detesting Lady Catherine. The rest of the paragraph is clear that Elizabeth thinks Charlotte is in an unpleasant situation but doesn't realize it yet.