What is the pathogenuc mechanism of brown pigment lipofuscin in muscle atrophy?
I think it is autophagy. Lysosomal degradation. Autophagocytosis.
Example of the brown pigment (lipofuscin) here:
!enter image description here
I am not sure if autophagy is the right answer to the "pathogenic" mechanism of atrophy.
**Is autophagy the pathogenic mechanism of atrophy?** Or **what pathogenic mechanism is involved if you see lipofuscin in the histologic slide?**