Artificial intelligent assistant

To understand clearly extraintestinal diseases Extradistestinal disease seems to prefer to "bowel" diseases, I think this is about diseases outside gastrointestinal tract so stomach. Consider diseases ulcerative colitis and Crohn's disease (enteritis) as examples. Colitis affects to colon, outside of small intestine, I think extraintestinal therefore. Crohn's disease (enteritis) however affects to the small intestine so I would think intestinal disease (but this clause is wrong) - it should be at least have extraintestinal manifestations. **What is the exact definition of the word _extra_ in intestinal diseases?**

Certain intestinal diseases have symptoms that appear concurrently in other systems of the body, but the bowel diseases _themselves_ are not extraintestinal.

> Extraintestinal manifestations of inflammatory bowel disease are prevalent in both ulcerative colitis and Crohn's disease. The most common manifestations involve the musculoskeletal and dermatologic systems. Other manifestations involve the hepatopan-creatobiliary system (eg, primary sclerosing cholangitis) as well as the ocular, renal, and pulmonary systems1.

One of the key differences between extraintestinal manifestations and comorbid conditions (though seemingly not a necessity, the article cites primary sclerosing cholangitis as an counterexample) is that the extraintestinal effects will subside once the disease of the bowel is treated.

1 Levine, J.S., Burakoff, R. (2011). Extraintestinal Manifestations of Inflammatory Bowel Disease. _Gastroenterol Hepatol (NY), 7_ (4), 235–241.

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