$$F (x)=\int_{5x}^2\sin (t^3)dt $$
put
$$G (X)=\int_0^X \sin (t^3)dt. $$
$t\mapsto \sin (t^3) $ is continuous at $\mathbb R$, thus $G $ is differentiable at $\mathbb R $ and By FTC, $$G'(x)=\sin (x^3) . $$
but
$$F (x)=G (2)-G (5x) $$
then by chain rule, $F $ is differentiable at $\mathbb R $ and
$$(\forall x\in \mathbb R)\;\; \; F'(x)=-(G'(5x ))\times 5$$
> $$=-5\sin (125x^3) $$