import re
a1 = "Extension=1200,Type=567,Port=S123,Name=Suzuki, Taro,Coverage_Path_1=,Coverage_Path_2="
b1 = "Extension=3089,Type=123,Port=S432,Name=OPS_Temp,Coverage_Path_1=,Coverage_Path_2="
print(re.sub(r'(Name.*?)(,+\s)(.*?,Coverage_Path_1)', r'\1_\3', a1))
print(re.sub(r'(Name.*?)(,+\s)(.*?,Coverage_Path_1)', r'\1_\3', b1))
#
Extension=1200,Type=567,Port=S123,Name=Suzuki_Taro,Coverage_Path_1=,Coverage_Path_2=
Extension=3089,Type=123,Port=S432,Name=OPS_Temp,Coverage_Path_1=,Coverage_Path_2=