`A() + B() + C/ + ()` is a common construction.
If A is a noun, AB means "as B as A", and the sentence can be translated as "No C is as B as A." or "There is no C that is more B than A." If A is a verb, AB means "B (enough) to A" or "B to the point where A happens", and the sentence is translated as "No C is B enough to A".
> *
> No one is as beautiful as she is.
> *
> There is no question that is easier than this one.
>
Therefore:
>
> Nothing is as unsettling as a den without my smell ingrained into it.
("unsettling") is a relative clause that modifies .