So, in your directed graph, there is an edge from 'x' to 'y' of weight 'a' iff there is an edge from 'y' to 'x' of weight 'a'. Call this graph 'G1'.
Convert 'G1' into an undirected graph 'G2' so that there is an edge from 'x' to 'y' of weight 'a' in G2 iff there is an edge from 'x' to 'y' of weight 'a' in G1.
The cost of a minimum spanning tree (MST) in G1 is necessarily equal to the cost of an MST in G2.
So, take G1 as input, convert it into G2 and feed it into Prim's algorithm. IT generates a MST on G1.
As for the second part of your Q, yes-- Prim's algorithm necessarily be less than or equal to the weight of that Hamiltonian path. If it weren't, i.e. if the Hamiltonian path is of less cost than the tree, the Hamiltonian path would be the MST itself since a simple path is also a tree. A contradiction.