Do acetyl-CoA, acetyl-CoA carboxylase and acetyl-glutamate carry any charge? Do the following compounds have any charge? If not, then why? If yes, is there any database that would give me this information if the compound is negatively or positively charged? The compounds are as follows: Acetyl-CoA Acetyl-CoA carboxylase Acetyl-glutamate I have searched and somehow I am getting more confused.

chemicalize.org is a good utility for predicting many molecular properties such as pKa, pI and charge. The Human Metabolome Database uses the same underlying software but tabulates some of the data (eg charge is explicitly stated).

Acetyl-CoA, for example, has a pI of 1.32 and charge of -4 at pH=7.4.

* * *

Your second link is to a portion of an enzyme (a serine residue that gets phosphorylated). Prediction of protein properties can be done with ProtParam.

Human Acetyl-CoA Carboxylase 1, for example, has a pI of 5.95 and charge of -39.