It depends upon the context of the problem. In your first example it appears that perhaps one intends to solve for $x$ but in the second example it appears than one does not intend to solve for $x$. In the first example one immediately obtains \begin{equation} \frac{1}{250-x}=Ce^t \end{equation} by having expressed the constant in the form $\ln C$. If one wished to solve the second example for $x$ it would be better to use $\ln C$ there as well.