anathema
/əˈnæθəmə; ə`næθəmə/ n
1 [U, C] detested person or thing 极讨厌的人或事物
Racial prejudice is (an) anathema to me. 我对种族偏见深恶痛绝.
2 [C] formal declaration of the Christian Church, excommunicating sb or condemning sth as evil （基督教把某人逐出教会或谴责某事物为邪恶的）咒诅.